Besides being one of the top 10 cancers in Singapore, nose cancer is also common in China, Taiwan and Hong Kong - and often hereditary in South Chinese communities around the world.
The Chinese (particularly Southern Chinese, like Cantonese, Hokkiens and Teochews) are genetically predisposed to nasopharyngeal carcinoma (NPC), one of the most common cancers in Singapore, China, Taiwan, Hong Kong and Chinese communities around the world. NPC is more common in men than in women. Tragically, NPC often occurs in the prime of life, between 30 and 50 years of age.
Studies have shown that the Epstein Barr Virus (EBV) is a likely cause, although the presence of EBV does not automatically mean one has or will have NPC. Other implicated factors are polycyclic hydrocarbons (compounds produced in the burning of fossil fuels, like charcoal), nitrosamines (chemicals in preserved foods, like salted fish) and poor hygiene. There is also a strong heredity factor. People with a family history of NPC are predisposed to it and should be particularly aware of early symptoms.
Symptoms of NPC
NPC often originates in the back of the nose and above the soft palate, so it is often not visible of noticeable until it is very large or when it causes other symptoms. Therefore, NPC is often diagnosed late. Those who are predisposed to NPC need to be aware of the early symptoms, such as:
Later-stage NPC symptoms include blocked nose, headache and problems with cranial nerves, eye-movement and vision. Eventually, the cancer may spread to the bones, lungs and liver.
Treatment – The Good News
The good news is that early-stage NPC, if treated promptly and properly, enjoys an extremely high cure rate. Accordingly, early detection is incredibly important. If detected early, the NPC may require only radiotherapy. Later stages may require both radiotherapy and chemotherapy. If the NPC fails to respond to radiotherapy or chemotherapy, surgery may be required.
Detection And Diagnosis:
Our Singapore ENT clinic specialises in the end-to-end management of all ear, nose, and throat conditions while keeping the best ENT practices in mind.